Originally Posted by battlerattle
Anything is feasable, depends more on your available funding, fab skills, and time and effort you are willing to put into it. For most it is probably way more expensive than its worth.
That said I have seen Boss 427's in Pintos, Blown 350s in VW bugs, and just about everything else you can imagine. If its your dream go for it, but do ALOT of research on what you will need to get it done!
Boss 429 or 427 SOHC?
I think it would be easier to bolt in the engine, trans and rear and adapt the rest of the truck, versus trying to adapt an entire body to a newer frame. As stated, anyhting is possible depending on your skill and/or wallet.