I had a '76 Silverado years ago, and was really my only truck experience. For the last 10 years or so I had a Jeep Cherokee which was still going strong (mechanically anyway) at 240,000 miles but was starting to have electrical problems.
I decided on a small truck, and was looking at the Toyota Tacoma. Then I did some research and figured out that there were not a lot of benefits to a mid-size truck. The gas mileage wasn't much better, the engine wasn't as powerful, and the bed's don't hold as much cargo. Add in the fact that Tacoma's go for crazy prices used, and I decided to get a full size truck.
Since I had such good experience with the Jeep, and it was also a Chrysler, I decided to get the Ram. It didn't hurt that the Ram is the best looking truck, either.
I bought a 2007 Ram 1500 Quad Cab 4x4 on eBay and I couldn't be happier!