You can pay someone like Hemifever to tune your truck - you get a tuner that plugs into the OBD2 port. But that doesn't allow you to do the tuning yourself - if that is what you want.
There is no standalone tuning/custom flashing system for these Dodges - yet - HPTuners is working on one, but it is not available for the public yet (still testing).
Your best bet is to pay a place like Hemifever to do a tune for you - its a couple hundred bucks, and he knows what he is doing. He is a sponsor on this site - PM him. http://www.hemifevertuning.com/SCT_p/sct-can.htm