not with a 75hp shot. there are guys running a 125-150hp shot on stock internals. as long as you set your timing correctly and don't run lean your transmission will probably let go first.
gotta make sure your always running good fuel and your fuel system can handle the extra needs for the hit. I know of a lot of guys in the LSX world that spray 150 through a stock engine but put in a Walbro 225 in just for the extra nitrous demands. You could also run a stand alone dedicated nitrous fuel tank, but that is $$$
2011 Big Horn 4x4 -SnowWhite-
1 7/8ths catless ARH ceramic coated longtubes - Sport mirrors-55W 5000K HID low and fogs-LED EVERYTHING
I think you must have a good bottle heater with a pressure adjustable shut off and a good nitrous gauge on the bottle and one you can see in the dash or post area. Next a good inline nitrous filter. Use only a wet kit with the better larger solinoids. I prefer a hand button usually in the gear shift area. A good visual arming switch that glows red when armed. I always used a good octane booster to stay on the safe side. Nitrous Express octane booster was my fav. My 2004 Hemi with Nitrous dyno numbers where 507 hp to the wheels. I ran it for 2 years with no issues. Nitrous user since 1993 with no blown motors. A good purge is a must also. I have ran both a single stage and a dual stage set-up but liked the dual stage with a delay timer best. I would leave on 75 hp with a 1 sec delay for stage 2 - 75 hp (total 150 hp) Usually mid 12,s.