There are a million threads on here about tuners/programmers.
If Superchips makes one for your truck/engine then I'd say definitely give it a shot. Now, you won't gain 100HP and a 5mpg but you'll definitely see an improvement.
I'm going to have the mods move this to the 5.9L engine sub-forum instead of the suspension sub-forum
JVC Arsenal KD, Bilstein 5100 adjustables [maxed], aFe Stage 2 Air Intake, Superchips 3865, Husky Floor Mats, Saddleman Camo Seat Covers, Flowmaster 40 Series Muffler SI/DO, 20 % Tint. 35x12.5x17 Federal Couragia M/T, 17x8.5 VTEC Warlord wheels, -12mm offest.